Podcast Archive

• Podcast July 7, 2023: BeatPain Utah: Partnering With Community Health Centers Within a Socio-Technical Framework (Julie Fritz, PhD, PT)
  This podcast continues the discussion with Dr. Julie Fritz as she discusses partnering with community health centers within a socio-technical framework through BeatPain Utah. Click on the recording below to listen to the podcast.  NIH Pragmatic Trials Collaboratory · Podcast 45: From Observational Studies to Pragmatic ...
• Podcast June 12, 2023: All of Us Research Program: Improving Health Through Diverse Technology, Huge Cohorts, and Precision Medicine (Joshua Denny, MD, MS)
  This podcast continues the discussion with Dr. Joshua Denny as he discusses improving health through the All of Us research program. Click on the recording below to listen to the podcast. NIH Pragmatic Trials Collaboratory · Podcast 46: All of Us Research Program NIH Pragmatic Trials ...
• Podcast April 14, 2023: From Observational Studies to Pragmatic Clinical Trials: Research in PCORnet®
  This podcast continues the discussion with Drs. Russell Rothman and Erin Holve as they discuss a decade of research in PCORnet®. Click on the recording below to listen to the podcast. NIH Pragmatic Trials Collaboratory · Podcast 45: From Observational Studies to Pragmatic Clinical Trials: Research in ...
• Podcast February 28, 2023: The Heartline Trial: A New Paradigm in Conducting Virtual Clinical Trials (C. Michael Gibson, MS, MD)
  This podcast continues the discussion with Dr. Michael Gibson as he discusses a new paradigm in conducting virtual clinical trials. Click on the recording below to listen to the podcast. NIH Pragmatic Trials Collaboratory · Podcast 44: The Heartline Trial: A New Paradigm in Conducting ...
• Podcast January 25, 2023: Ethical Considerations When Vulnerable Populations are Subjects in Pragmatic Clinical Trials (Emily A. Largent, JD, PhD, RN)
  This podcast continues the discussion with Dr. Emily Largent as she discusses ethical considerations for vulnerable populations participating in pragmatic clinical trials. Click on the recording below to listen to the podcast. NIH Pragmatic Trials Collaboratory · Podcast 43: Ethical Considerations for Vulnerable Populations in ...
• Podcast July 8, 2022: FDA Draft Guidance on Real-World Evidence (John Concato, MD, MS, MPH)
  This podcast continues the discussion with Dr. John Concato as he discusses the FDA draft guidance on real-word evidence. Click on the recording below to listen to the podcast. NIH Pragmatic Trials Collaboratory · Podcast 42: FDA Draft Guidance on Real-World Evidence Want to hear more? ...
• Podcast January 19, 2022: Searching for a Unicorn: Understanding Stakeholder Perspectives When Selecting Outcomes for Outpatient Trials (Christopher Lindsell, PhD)
  This podcast continues the discussion with Dr. Christopher Lindsell as he discusses research outcomes and the importance of choosing the correct outcome. Click on the recording below to listen to the podcast. NIH Collaboratory · Podcast 41: Searching for a Unicorn: Selecting Outcomes for Outpatient Trials Want to ...
• Podcast August 5, 2021: Survivor Corps: Long-Term COVID-19 Patient Engagement (Diana Berrent, JD; Natalie Lambert, PhD; Nick Guthe)
  This podcast continues the discussion with Diana Berrent, JD, and Nick Guthe, both of Survivor Corps, and Natalie Lambert, PhD, of the Indiana University School of Medicine, as they describe best practices for medical professionals treating patients experiencing debilitating effects of COVID-19. Click on the recording ...
• Podcast August 2, 2021: Diversity Workshop Series: Increasing Diversity in Pragmatic Clinical Trials (Dr. Boineau, Dr. Chambers, Dr. Curtis, Dr. O’Brien, Dr. Weber, Dr. Zimmerman)
  This podcast summarizes the series on ‘Inclusion of Diverse Participants in Pragmatic Clinical Trials’ with a panel discussion with Dr. Robin Boineau, Dr. David Chambers, Dr. Lesley Curtis, Dr. Emily O’Brien, Dr. Wendy Weber, and Dr. Kanecia Zimmerman. Click on the recording below to listen to ...
• Podcast June 2, 2021: Online Recruitment in the Era of COVID-19: Pitfalls and Progress (Megan L. Ranney, MD, MPH)
  This podcast continues the discussion with Dr. Adrian Hernandez and Dr. Megan L. Ranney about using digital technologies in clinical trials and best practices for online participant recruitment. Click on the recording below to listen to the podcast. NIH Collaboratory · Podcast 38: Online Recruitment in the ...
• Podcast April 1, 2021: Data and Safety Monitoring Boards for Trials of COVID-19 Vaccines: The Challenges (Susan S. Ellenberg, PhD)
  In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Adrian Hernandez speaks with Dr. Susan Ellenberg of the University of Pennsylvania about the challenges encountered by the Data and Safety Monitoring Board overseeing a group of COVID-19 vaccine trials under the National Institutes ...
• Podcast March 1, 2021: Beyond Politics: Promoting COVID Vaccination in the United States (Kevin Schulman, MD)
  In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Adrian Hernandez speaks with Dr. Kevin Schulman of Stanford about strategies for promoting widespread COVID-19 vaccination in the United States. Click on the recording below to listen to the podcast. NIH Collaboratory · Podcast 36: Beyond ...
• Podcast January 12, 2021: HERO-TOGETHER (Emily O’Brien, PhD)
  In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Adrian Hernandez speaks with Dr. Emily O’Brien of the Duke Clinical Research Institute about the HERO-TOGETHER study that is evaluating how people do over time after receiving the COVID-19 vaccine. Click on the recording below ...
• Podcast November 6, 2020: Lessons from Virtual Trials in Time of a Pandemic (David Boulware, MD, MPH)
  This episode of the NIH Collaboratory Grand Rounds podcast follows the conversation between Dr. David Boulware and Dr. Adrian Hernandez as they discuss the complexities of conducting virtual clinical trials during the COVID-19 pandemic. Click on the recording below to listen to the podcast. NIH Collaboratory · ...
• Podcast August 7, 2020: The Democratization of Medicine: Open Access, Social Media, AI, Apps, and Empowering the Patient as the Future of Clinical Research (C. Michael Gibson, MS, MD)
  This episode of the NIH Collaboratory Grand Rounds podcast follows the conversation between Dr. C. Michael Gibson and Dr. Adrian Hernandez as they discuss how open access, patient empowerment, social media, and digital health are transforming clinical trials. Click on the recording below to listen to ...
• Podcast July 8, 2020: Reflection on Advances at the Intersection of Digital Health, Electronic Health Records, and Pragmatic Clinical Trials (Wendy Weber, ND, PhD, MPH; Lesley Curtis, PhD; Patrick Heagerty, PhD; Keith Marsolo, PhD)
  This episode of the NIH Collaboratory Grand Rounds Podcast, led by Wendy Weber, ND, PhD, MPH, reflects on the Grand Rounds EHR workshop series, “Advances at the Intersection of Digital Health, Electronic Health Records, and Pragmatic Clinical Trials.” The podcast features panelists Lesley Curtis, PhD, ...
• Podcast May 8, 2020: Advances at the Intersection of Digital Health, Electronic Health Records, and Pragmatic Clinical Trials: Real World Evidence: Contemporary Experience and Future Directions (Joshua C. Denny, MD, MS)
  This episode of the NIH Collaboratory Grand Rounds podcast follows the conversation on Electronic Health Records (EHRs) between Dr. Lesley Curtis and Dr. Joshua C. Denny, Chief Executive Officer of the All of Us Research Program. The discussion covers questions on Dr. Denny’s early experience ...
• Podcast May 1, 2020: Can the COVID-19 Crisis Lead to Reformation of the Evidence Generation Ecosystem? (Robert Califf, MD, MACC)
  In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Lesley Curtis speaks with Dr. Robert Califf, Head of Strategy and Policy at Verily Life Sciences and Google Health about whether the COVID-19 crisis can lead to reformation of the current healthcare delivery system. ...
• Podcast March 6, 2020: Creating a Learning Health System Through Randomization (Leora Horwitz, MD, MHS)
  In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Adrian Hernandez speaks with Dr. Leora Horwitz of NYU Langone Health about creating a Learning Health System through randomization. Click on the recording below to listen to the podcast. Want to hear more? View the full ...
• Podcast February 7, 2020: Using Nudges to Improve the Delivery of Health Care (Mitesh S. Patel, MD, MBA)
  In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Adrian Hernandez speaks with Dr. Mitesh Patel of University of Pennsylvania about using nudges in a healthcare system to “steer medical decision-making toward higher value and improved patient outcomes.” Click on the recording below to ...
• Podcast November 22, 2019: It’s Time to Learn From Patients Like Mine (Nigam H. Shah, MBBS, PhD)
  In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Adrian Hernandez sits down with Dr. Nigam Shah of Stanford University to discuss an informatics service called “Green Button,” which searches across diagnosis and procedure codes, concepts extracted from clinical notes, laboratory test results, ...
• Podcast October 18, 2019: Playing with FHIR–Innovative Use Cases for the New REDCap EHR Integration Module (Paul Harris, PhD)
  In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Adrian Hernandez sits down with Dr. Paul Harris to discuss REDCap integration with Fast Healthcare Interoperability Resources (FHIR). In the discussion, Harris covers past challenges of Electronic Health Record and Electronic Data Capture integration, ...
• Podcast October 1, 2019: Preparing for Clinical Trial Data Sharing and Re-use: The New Reality for Researchers (Rebecca Li, PhD, Frank Rockhold, PhD)
  In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Adrian Hernandez sits down with Drs. Rebecca Li and Frank Rockhold to discuss clinical trial data sharing and re-use. In the discussion, Li and Rockhold highlight benefits, potential fears, and the future of data sharing and open ...
• Podcast August 21, 2019: Digital in Trials: Improving Participation and Enabling Novel Endpoints (Craig Lipset)
  In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Kevin Weinfurt sits down with Craig Lipset to discuss the role and impact of digital in trials. In the discussion, Lipset highlights displacement and its impact on traditional research models, the concept of digital twins, and ...
• Podcast June 26, 2019: Good Clinical Practice Guidance and Pragmatic Trials: Balancing the Best of Both Worlds in the Learning Health System (Robert Mentz, MD)
  In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Adrian Hernandez sits down with Dr. Rob Mentz to discuss balancing Good Clinical Practice Guidance and Pragmatic Trials in the Learning Health System. In the discussion, Dr. Mentz covers key challenges with good clinical practice (GCP), ...
• Podcast April 16, 2019: Development of Harmonized Outcome Measures for Use in Research and Clinical Practice (Michelle Leavy, MPH, Elise Berliner, PhD)
  In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Adrian Hernandez sits down with Dr. Elise Berliner and Michelle Leavy to discuss the Development of Harmonized Outcome Measures for Use in Research and Clinical Practice. In the discussion, Dr. Berliner and Leavy explain the outcome measures ...
• Podcast February 19, 2019: Paramedic Airway Management in Out-of-Hospital Cardiac Arrest – The Pragmatic Airway Resuscitation Trial (PART) (Henry Wang, MD, MS)
  In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Adrian Hernandez sits down with Dr. Henry Wang to discuss The Pragmatic Airway Resuscitation Trial (PART); a trial that took 10 years of hard work and diligence to complete. In his discussion, Dr. Wang explains the importance ...
• Podcast January 29, 2019: A Learning Health System Story: Perinatal Outcomes Associated with a Major Change in Gestational Diabetes Screening (Sascha Dublin, MD, PhD, Gaia Pocobelli, PhD)
  In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Kevin Weinfurt sits down with Dr. Sascha Dublin and Dr. Gaia Pocobelli to discuss their study that focused on perinatal outcomes associated with a major gestational diabetes screening. In their conversation, Drs. Dublin and Pocobelli explain ...
• Podcast December 5, 2018: Validating a Computable Phenotype: Should Results Change a Trial’s Pre-Specified Primary Outcome? (Gregory E. Simon, MD, MPH, Susan M. Shortreed, PhD)
  In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Lesley Curtis speaks with Dr. Gregory Simon and Dr. Susan Shortreed of the Kaiser Permanente Washington Health Research Institute. In their conversation, Drs. Curtis, Simon, and Shortreed discuss computable phenotypes and if results should change a trial’s ...
• Podcast November 20, 2018: Data Linkage Within, Across, and Beyond PCORnet (Thomas W. Carton, PhD, MS, Keith Marsolo, PhD)
  In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Lesley Curtis speaks with Dr. Tom Carton, of the REACHnet Clinical Data Research Network, and Dr. Keith Marsolo, of the Duke School of Medicine, regarding data linkage within, beyond, and across The National Patient-Centered Clinical Research ...
• Podcast November 7, 2018: MDEpiNet RAPID and SPEED Projects: Leveraging Real World Evidence to Get Better, Faster, Cheaper Medical Devices for Physicians and Patients (Renee Mitchell, MT, CLS, Terrie Reed, MSIE, Roseann White, MA)
  In this episode of the NIH Collaboratory Grand Rounds podcast, Renee Mitchell, Terrie Reed, and Roseann White discuss the MDEpiNet RAPID and SPEED Projects. In their conversation with Dr. Adrian Hernandez, Renee, Terrie, and Roseann discuss the concept behind the projects, the collaborative nature, associated challenges, next ...
• Podcast October 1, 2018: Returning Individual Research Results to Participants: Guidance for a New Research Paradigm (Jeffrey Botkin, MD, MPH, Consuelo Wilkins, MD, MSCI)
  In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Jeffrey Botkin and Dr. Consuelo Wilkins discuss returning individual research results to participants. In their conversation with Dr. Adrian Hernandez, Drs. Botkin and Wilkins emphasize the importance of returning results to participants, the present challenges, ...
• Podcast August 7, 2018: A Digital Pragmatic Direct-to-Participant Clinical Trial for Identifying Underdiagnosed Atrial Fibrillation in a Large Health Plan Population (Steven Steinhubl, MD)
  In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Steven Steinhubl discusses a digital and pragmatic clinical trial, mSToPS, that explores underdiagnosed atrial fibrillation in a large health plan population. In his conversation with Dr. Lesley Curtis, Dr. Steinhubl discusses what lessons were learned ...
• Podcast July 17, 2018: Clinical Trial Participants’ Views of the Risks and Benefits of Data Sharing (Michelle Mello, JD, PhD)
  In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Michelle Mello discusses a study she and Dr. Steven Goodman recently conducted to determine how clinical trial participants think about having their participant-level data widely shared. In her discussion with Dr. Lesley Curtis, Dr. Mello ...
• Podcast July 3, 2018: Policy & Priorities: Rethinking University Research with State Data (Aaron McKethan, PhD)
  In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Aaron McKethan discusses the idea of rethinking research with state-level data. Dr. McKethan serves as a faculty member in the Department of Population Health Sciences at Duke University and is the Chief Data and Analytics Officer ...
• Podcast June 22, 2018: Research at Scale – Exploring What is Possible with High-Quality Real-World Data. Examples from Flatiron Health. (Amy Abernethy, MD, PhD)
  In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Amy Abernethy discusses research at scale, with examples from Flatiron Health. In her discussion with moderator Adrian Hernandez, Dr. Abernethy focuses on the goals of Flatiron Health, approaches for building data-sets and underlying infrastructure, what’s next ...
• Podcast May 23, 2018: Launching the NESTcc Data Network to Improve the use of Real-World Evidence in the Medical Device Ecosystem (Rachael Fleurence, PhD)
  In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Rachael Fleurence, Executive Director of the National Evaluation System for health Technology Coordinating Center (NESTcc) and the Medical Device Innovation Consortium (MDIC), discusses the mission, challenges, and long term goals of NESTcc with moderator ...
• Podcast April 17, 2018: OHDSI: Drawing Reproducible Conclusions From Observational Clinical Data (George Hripcsak, MD, MS)
  In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. George Hripcsak, Chair of the Bioinformatics Department at Columbia University, discusses the Observational Health Data Sciences and Informatics (OHDSI) Program with moderator Dr. Adrian Hernandez. He describes the program’s vision to create accessible and reliable ...
• Podcast April 9, 2018: Data Science in the Era of Data Ubiquity (Robert Califf, MD)
  In this episode of the NIH Collaboratory Grand Rounds podcast, moderator Dr. Adrian Hernandez speaks with former FDA Commissioner and current Duke Forge Director Dr. Robert Califf about the opportunities and challenges for data science in an era where data are everywhere. Now that mobile ...
• Podcast March 22, 2018: Straight from the Source: Clinicians’ Views on Participating in CER/PCOR (Sean Tunis, MD, MSc; Ellen Tambor, MA)
  In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Sean Tunis and Ellen Tambor of the Center for Medical Technology Policy (CMTP) speak with moderator Dr. Kevin Weinfurt about their findings on clinician attitudes on comparative effective research (CER) and patient-centered outcomes research (PCOR). The speakers discuss ...
• Podcast February 16, 2018: Considerations for the Return of Genomic Results (Andrew Faucett, MS, LGC)
  In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Andrew Faucett of Geisinger speaks with moderator Dr. Lesley Curtis about the return of genomic results. A key consideration for returning results of this type of research to patients and clinicians is how to scale it, as there ...
• Podcast January 5, 2018: IMPACT-AFib: An 80,000 Person Randomized Trial Using the Sentinel Initiative Platform (Richard Platt, MD, MS; Christopher Granger, MD, FACC, FAHA)
  In this episode of the NIH Collaboratory Grand Rounds podcast, Drs. Richard Platt and Christopher Granger speak with moderator Dr. Adrian Hernandez about the IMPACT-AFib atrial fibrillation trial and the role of the FDA’s Sentinel Inititative.  In this trial, researchers used Sentinel pharmacy data to find eligible patients ...
• Podcast December 8, 2017: Data and Safety Monitoring in Pragmatic Clinical Trials (Greg Simon, MD, MPH, and Susan Ellenberg, PhD)
    In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Greg Simon, principal investigator of the Suicide Prevention Outreach Trial (SPOT), and Susan Ellenberg, a member of the Collaboratory Ethics and Regulatory Core, speak with moderator Dr. Adrian Hernandez about the factors that determine the need for ...
• Podcast November 14, 2017: Moderators’ Edition: Discussion of the Future of the NIH Collaboratory
  In this episode of the NIH Collaboratory Grand Rounds podcast, Drs. Adrian Hernandez and Kevin Weinfurt, two NIH Collaboratory Co-PIs and podcast moderators, discuss their predictions and hopes for the NIH Collaboratory in the next year. Click on the recording below to listen to the podcast.   We ...
• Podcast October 27, 2017: Bringing Machine Learning to the Point of Care to Improve Suicide Prevention (Greg Simon, MD, MPH)
  In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Greg Simon of the Kaiser Permanente Washington Health Research Institute speaks with the NIH Collaboratory’s Dr. Lesley Curtis about the integration of machine learning into suicide prevention. Click on the recording below to listen to the podcast.   Want to ...
• Podcast October 6, 2017: Health Is More Than Healthcare (Karen DeSalvo, MD, MPH, MSc)
  In this second episode of the NIH Collaboratory Grand Rounds podcast, Dr. Karen DeSalvo, former acting Assistant Secretary for Health and Human Services, speaks with the NIH Collaboratory’s Dr. Kevin Weinfurt about the factors other than healthcare systems than impact the health of our communities. Click on the recording ...
• Podcast September 29, 2017: Preprints: What, Why Not, and How (Harlan Krumholz, MD)
  In this first episode of the NIH Collaboratory Grand Rounds podcast, Dr. Harlan Krumholz of Yale University Medical Center speaks with the NIH Collaboratory’s Dr. Adrian Hernandez about the ways preprint servers can help accelerate scientific progress through greater access to research results. Click on the ...