Speaker
Russell Rothman, MD, MD, MPP, Professor, Internal Medicine, Pediatrics, & Health Policy
Vice President for Population Health Research
Director, Center for Health Services Research
Vanderbilt University Medical Center
Topic
Leveraging Informatics in Pragmatic Research: Initial Experience in PCORnet
Keywords
Pragmatic clinical trial; Clinical research; Patient engagement; PCORI; PCORnet; Informatics; CDRN; Vanderbilt
Key Points
- PCORnet includes Clinical Data Research Networks (CDRNs) for sharing informatics tools and engaging stakeholders.
- The MidSouth CDRN, including Vanderbilt Medical Center and the Duke School of Medicine, comprises electronic health records of more than 9 million patients.
- Novel informatics tools can quickly run queries, analyze health data, and collect survey data on patient-reported outcomes.
- The ADAPTABLE study “disrupts the norm” from traditional trials with the PCORnetCommon Data Model and its patient-directed e-consent process.
Discussion Themes
Additional informatics tools available include expanded clinical decision support tools to help providers at the point of care, and expanded BioVu and Tissue repository for biologic studies
Regulatory efficiencies such as a central IRB and shared contracting templates should be utilized when possible
PCORnet can pull Medicare claims data to capture hospital or ED visit, as well as gather self-reported outcome data from patients directly, to gain a more complete picture
PCORnet has a wide variety of group participating in its network, both academic and non-academic, to ensure diversity in population recruitment
For More Information
For more information on PCORnet, visit http://www.pcornet.org/; on the MidSouth CDRN, visit https://midsouthcdrn.mc.vanderbilt.edu/; on the BioVU, visit https://victr.vanderbilt.edu/pub/biovu/?sid=194?
Tags
#pctGR, #PragmaticTrials, #ClinicalResearch
@PCTGrandRounds, @Collaboratory1, @PCORnetwork, @VUMChealth